International Journal of Scientific Research and Engineering Development

Holoptelea integrifolia, prominently observed as an ethnomedicine, has gained a significant interest in research. The interaction between conventional knowledge with advanced research enhances its utility for developing safe, efficient, and sustainable therapeutics. Few characteristics of the plant are the unique anatomy of its leaves, bark, seeds and fruits along with diverse bioactive compounds including glycosides, flavonoids, phenols, saponins, triterpenoids, and phytosterols. The secondary metabolites gave the plant its alleged properties such as antibacterial, antifungal, antioxidant, anti-inflammatory, analgesic, antidiabetic, antiviral, anthelmintic, and wound healing activity. Recently employed analytical techniques have identified the key phytoconstituents such as β-amyrin, lupeol, friedelin, and β-sitosterol, highlighting their therapeutic significance. The evidence positions Holoptelea integrifolia as a valuable candidate for drug development and shows that it is a promising candidate after ensuring the safety, efficacy and standardisation. This review critically evaluates the pharmaceutical potential of Holoptelea integrifolia, highlighting it as a source for novel therapeutic agents including the comprehensive analysis of its morphological characteristics, phytochemical studies, ethnomedicinal uses, pharmacological activities and the way it can be used in the future.

Priti Surwase, Vaishnavi Thakur, Shruti Patil, Aarti Kute, Dr.Shrutika Patil,"Exploring the Ethnopharmacological Potential of Holoptelea integrifolia: Phytochemical and Pharmacological Perspectives" International Journal of Scientific Research and Engineering Development, V9(2): Page(1474-1483) Mar-Apr 2026. ISSN: 2581-7175. www.ijsred.com. Published by Scientific and Academic Research Publishing.