International Journal of Scientific Research and Engineering Development

Introduction:
Progesterone is a critical hormone for female reproductive health, with therapeutic uses in managing conditions like irregular cycles, endometriosis, PCOS, and infertility. This non-interventional observational study assessed real-world usage patterns and patient-reported outcomes of progesterone therapy.
Materials and Methods:
A cross-sectional study of 100 females prescribed progesterone was conducted. Participants were recruited via convenience sampling and completed questionnaires on demographics, medical history, treatment details, effectiveness, and symptom relief. Physiological parameters were recorded. Data were analysed using descriptive statistics.
Results:
The cohort had a mean age of 36.89 ± 9.51 years. Most participants were menstruating (53%), with common conditions being endometriosis (37%) and PCOS (26%). Treatment was primarily oral (84%), with perfect adherence reported. A high proportion (84%) found progesterone somewhat or very effective. Key benefits included improved menstrual regularity, increased fertility (31%), reduced period pain (31%), and reduced bleeding (22%). Furthermore, 62% reported improved pregnancy outcomes.
Conclusion:
This real-world evidence confirms the importance of progesterone in effectively managing a spectrum of reproductive health disorders, with high patient satisfaction and adherence. It highlights its role in alleviating symptoms and improving fertility, supporting its continued use in clinical practice. Further investigation into long-term outcomes is warranted.

Santhi Sri, M.Chandu Supriya, Shaik Karimulla, T.Varaprasad, Faruk Abdullah,"A Non-Interventional Data Collection Study to Determine The Risk Factors Associated with Diabetes and Hypertension" International Journal of Scientific Research and Engineering Development, V9(1): Page(988-993) Jan-Feb 2026. ISSN: 2581-7175. www.ijsred.com. Published by Scientific and Academic Research Publishing.