International Journal of Scientific Research and Engineering Development

Metabolic disorders, including diabetes mellitus, obesity, dyslipidemia, and metabolic syndrome, are major global health challenges associated with lifestyle changes and dietary habits. Conventional pharmacotherapy is often linked with adverse effects and long-term complications, prompting increased interest in nutraceuticals derived from medicinal plants as safer and effective alternatives. Nutraceuticals are bioactive compounds present in foods or herbal sources that provide health benefits beyond basic nutrition. Medicinal plants are rich in phytochemicals such as polyphenols, flavonoids, alkaloids, terpenoids, saponins, and dietary fibers, which exhibit antioxidant, anti-inflammatory, hypoglycemic, hypolipidemic, and insulinsensitizing activities. These bioactive constituents modulate key metabolic pathways involved in glucose and lipid metabolism, oxidative stress, and chronic inflammation, thereby contributing to the prevention and management of metabolic disorders. This review summarizes the therapeutic potential of nutraceuticals obtained from medicinal plants, their mechanisms of action, and their role in managing metabolic disorders. Additionally, challenges related to bioavailability, safety, standardization, and regulatory aspects are discussed. The integration of plant-based nutraceuticals into daily diets and therapeutic strategies may offer a promising approach for improving metabolic health and reducing disease burden.

K.Malleswaru, Dr.D.Rama Brahma Reddy, K.Sirisha, "A Review on Nutraceuticals of Medicinal Plants for Metabolic Disorders" International Journal of Scientific Research and Engineering Development, V8(6): Page(2652-2660) Nov-Dec 2025. ISSN: 2581-7175. www.ijsred.com. Published by Scientific and Academic Research Publishing.