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Nano Medicine Approach for Alzheimer’s Disease

	International Journal of Scientific Research and Engineering Development (IJSRED)	Full Text:
	Published Issue : Volume-3 Issue-6
	Year of Publication : 2020
	Unique Identification Number : IJSRED-V3I6P99
	Authors : Lisha Deb, Anoushka Das, Purvi Patawri, Abhilipsa Dash, Tiyasa Guha
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Abstract :

Alzheimer’s is a neurodegenerative disease that interferes with person’s memory, thinking and behaviour. It is characterized by the cognitive inability of the affecter’s brain, manifested due to the accumulation of β-amyloid, the formation of hyper phosphorylated neurofibrillary tangles, and a malfunctioned cholinergic system. Over 35 million people worldwide are affected by this ailment. Although, there is no conclusive treatment for humans yet, a promising approach is represented by nanotechnology. Nano medicine-based approaches have opened an area via theranostics of Alzheimer’s disease, which are able to target and deliver drugs across the blood–brain barrier (BBB). This review article attempts to provide an insight on theranostic approaches of Alzheimer’s disease, taking into account five different nanoparticles, namely, Gold, Cerium Oxide, Iron Oxide, PLGA and Selenium.